16th Annual Screen Actors Guild Awards (2010)
- Date of Ceremony: Saturday, January 23, 2010
- For performances seen in: 2009
- Nominations Announcement: Thursday, December 17, 2009
- Location: Shrine Auditorium, Los Angeles, CA
The 16th Annual Screen Actors Guild Awards took place on Saturday, January 23, 2010 at the Shrine Auditorium in Los Angeles.
Sandra Bullock presented the Life Achievement Award to Betty White, her co-star in The Proposal.
- The Closer: 3
- 30 Rock: 3
- Dexter: 3
- Up in the Air: 3
- Precious: Based on the Novel Push by Sapphire: 3
- Inglourious Basterds: 3